In their landmark 1973 study, Block et al. performed an analysis of the development of 5-flurocytosine resistance in the pathogen Cryptococcus neoformans. a) How did they determine if resistance is induced through interaction between the pathogen and the anti-fungal agent?b) How could you have used this approach to determine whether exposure to creates lys mutants?c) What result should you anticipate, and why?
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